2006

Motola, D., Cummins, C.L., Rottiers, V., Sharma, K., Sunino, K., Xu, E., Auchus, R., Antebi, A., and Mangelsdorf, D. (2006). Identification of hormonal ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell 124, 1209-23.

Huber, T.B., Schermer, B., Müller, R.U., Höhne, M., Bartram, M., Calixto, A., Hagmann, H., Reinhardt, C., Koos, F., Kunzelmann, K., Shirokova, E., Krautwurst, D., Harteneck, D., Simons, M., Pavenstädt, H., Kerjaschki, D., Thiele, C., Walz, G., Chalfie, M., and Benzing, T. (2006). Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc. Natl. Acad. Sci. U.S.A. 103, 17079-17086.

Baumgartl, J., Baudler, S., Scherner, M., Babaev, V., Makowski, L., Suttles, L., McDuffie, M., Tobe, K., Kadowaki, T., Fazio, S., Kahn, C.R., Hotamisligil, G.S., Krone, W., Linton, M.R., Brüning J.C. (2006). Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. Cell Metab. 3, 247-256.

Krones-Herzig, A., Mesaros, A., Metzger, D., Ziegler, A., Lemke, U., Brüning, J. C., and Herzig, S. (2006). Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1. J. Biol. Chem. 281, 3025-3029.

Sheffler, D. J., Kroeze, W. K., Garcia, B. G., Deutch, A. Y., Hufeisen, S. J., Leahy, P., Brüning J.C., and Roth, B. L. (2006). p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Proc. Natl. Acad. Sci. USA 103, 4717-4722.

Plum, L., Ma, X., Hampel, B., Balthasar, N., Coppari, R., Munzberg, H., Shanabrough, M., Burdakov, D., Rother, E., Janoschek, R., Alber, J., Belgardt, B. F., Koch, L., Seibler, J., Schenk, F., Fekete, C., Suzuki, A., Mak, T.W., Krone, W., Horvath, T. L., Ashcroft, F. M., and Brüning J.C. (2006). Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. J. Clin. Invest. 116, 1886-1901.

Müller, T., Strösser, J., Buchinger, S., Nolden, L., Wirtz, A., Krämer, R., and Burkovski, A. (2006). Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: towards the identification of nitrogen control signals. J. Biotechnol. 126, 440-453.

Laubinger, S., Marchal, V., Gentilhomme, J., Wenkel, S., Adrian, J., Jang, S., Kulajta, C., Braun, H., Coupland, G., and Hoecker, U. (2006). Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability. Development 133, 3213-3222. (A 1, C 2)

Wenkel, S., Turck, F., Singer, K., Gissot, L., Le Gourrierec, J., Samach, A., and Coupland, G. (2006). CONSTANS and the CCAAT box binding complex share a functionally important domain and interact to regulate flowering of Arabidopsis. Plant Cell 18, 2971-2984.

Chen, Q., Thorpe, J., Dohmen, R.J.., Li, F., and Keller, J.N. (2006). Ump1 extends yeast lifespan and enhances viability during oxidative stress: Central role for the proteasome? Free Radic. Biol. Med. 40, 120-126.

Kevei, E., Gyula, P., Hall, A., Kozma-Bognar, L., Kim, W.Y., Eriksson, M.E., Toth, R., Hanano, S., Feher, B., Southern, M.M., Bastow, R.M., Viczian, A., Hibberd, V., Davis, S.J., Somers, D.E., Nagy, F., and Millar, A.J. (2006). Forward genetic analysis of the circadian clock separates the multiple functions of ZEITLUPE. Plant Physiol. 140, 933-945.

Fittinghoff, K., Laubinger, S., Nixdorf, M., Fackendahl, P., Baumgardt, R.L., Batschauer, A., and Hoecker, U. (2006). Functional and expression analysis of Arabidopsis SPA genes during seedling photomorphogenesis and adult growth. Plant J. 47, 577-590.

Laubinger, S., Marchal, V., Gentilhomme, J., Wenkel, S., Adrian, J., Jang, S., Kulajta, C., Braun, H., Coupland, G., and Hoecker, U. (2006). Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability. Development 133, 3213-3222. (C 2, A 1)

Grelle, G., Kostka, S., Otto, A., Kersten, B., Genser, K.F., Müller, E.C., Walter, S., Boddrich, A., Stelzl, U., Hanig, C., Volkmer-Engert, R., Landgraf, C., Alberti, S., Höhfeld, J., Strodicke, M., and Wanker, E.E. (2006). Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays. Mol. Cell. Proteomics 5, 234-244.

Rybakin, V., Gounko, N.V., Späte, K., Höning, S., Majoul, I.V., Duden, R., and Noegel, A.A. (2006). Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi. J. Biol. Chem. 281, 31070-31078.

Martens, S., and Howard, J.C. (2006). Interferon-inducible GTPases. Annu. Rev. Cell Dev. Biol. 22, 559-589. Review

Spitzer, C., Schellmann, S., Sabovljevic, A., Shahriari, M., Keshavaiah, C., Müller, S., Hanisch, F.-G., Bechtold, N., Herzog, M., Hülskamp, M. (2006). The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis. Development 133, 4679-4689.

Nowack, M.K., Grini, P.E., Jakoby, M.J., Lafos, M., Koncz, C., and Schnittger, A. (2006). A positive signal from the fertilisation of the egg cell sets off endosperm proliferation in angiosperm embryogenesis. Nature Genet. 38, 63-67.

Shimotohno, A., Ohno, R., Bisova, K., Sakaguchi, N., Huang, J., Koncz, C., Uchimiya, H., and Umeda, M. (2006). Diverse phosphoregulatory mechanisms controlling cyclin-dependent kinase-activating kinases in Arabidopsis. Plant J. 47, 701-710.

Graef, M., and Langer, T. (2006). Substrate specific consequences of central pore mutations in the i-AAA protease Yme1 on substrate engagement. J. Struct. Biol. 156, 101-108.

Nolden, M., Kisters-Woike, B., Langer, T., and Graef, M. (2006). Quality control in the mitochondrion. Topics Curr. Gen. 16, 119-147. Review

Rugarli, E.I., and Langer, T. (2006). Translating m-AAA protease function in mitochondria to hereditary spastic paraplegia. Trends in Mol. Med. 12, 262-269. Review

Tatsuta, T., and Langer, T. (2006). Studying proteolysis within mitochondria. Methods in Molecular Biology 372, 343-360. Review

Escobar-Henriques, M., and Langer, T. (2006). Mitochondrial shaping cuts. Biochim. Biophys. Acta 1763, 422-429. Review

Fulda, S., Mikkat, S., Huang, F., Huckauf, J., Marin, K., Norling, B., and Hagemann, M. (2006). Proteome analysis of salt stress response in the cyanobacterium Synechocystis sp. strain PCC 6803. Proteomics 6, 2733-2745.

Csiszar, A. (2006). Structural and functional diversity in adapter proteins involved in tyrosine kinase signalling. Bioessays 28, 465-479. Review (A 7)

Azevedo, C., Betsuyaku, S., Peart, J., Takahashi, A., Noël, L., Sadanandom, A., Casais, C., Parker, J.E., and Shirasu, K. (2006). Role of SGT1 in resistance protein accumulation in plant immunity. EMBO J. 25, 2007-2016. (B 4)

Bartsch, M., Gobbato, E., Bednarek, P., Debey, S., Schultze, J.L., Bautor, J., and Parker, J.E. (2006). Salicylic acid independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell 18, 1038-1051. (B 7)

Brodersen, P., Petersen, M., Nielsen, H.B., Zhu, S., Newman, M.A., Shokat, K.M., Rietz, S., Parker, J.E., and Mundy, J. (2006). Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4. Plant J. 47, 532-546. (B 7)

Nenci, A., Huth, M., Funteh, A., Schmidt-Supprian, M., Bloch, W., Metzger, D., Chambon, P., Rajewsky, K., Krieg, T., Haase, I., and Pasparakis, M. (2006). Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signalling. Hum. Mol. Genet. 15, 531-542.

van Loo, G., De Lorenzi, R., Schmidt, H., Huth, M., Mildner, A., Schmidt-Supprian, M., Lassmann, H., Prinz, M.R., and Pasparakis, M. (2006). Inhibition of transcription factor NF-?B in the central nervous system ameliorates autoimmune encephalomyelitis in mice. Nat. Immunol. 7, 954-961.

Victoratos, P., Lagnel, J., Tzima, S., Alimzhanov, M.B., Rajewsky, K., Pasparakis, M., and Kollias, G. (2006). FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses. Immunity 24, 65-77.

Kunzelmann, S., Praefcke, G.J.K., and Herrmann, C. (2006). Transient kinetic investigation of GTP hydrolysis catalysed by interferon-gamma induced human guanylate binding protein 1 (hGBP1). J. Biol. Chem. 281, 28627-28635.

Ghosh, A., Praefcke, G.J.K., Renault, L., Wittinghofer, A., and Herrmann, C. (2006). ?How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP. Nature 440, 101-104.

Böhmer, M., Kurth, J., Witte, C.-P., and Romeis, T. (2006). Function of plant calcium-dependent protein kinases in the activation of abiotic and pathogen-related stress responses and its potential application in the generation of stress-resistant plants. In: Floriculture, Ornamental and Plant Biotechnology, Global Science Books Vol III, 367-372. Review

Kim, E.Y., Schrader, N., Smolinsky, B., Bedet, C., Vannier, C., Schwarz, G., and Schindelin, H. (2006). Deciphering the structural framework of glycine receptor anchoring by gephyrin. EMBO J. 25, 1385-1395. (A 11)

Xiang, S., Kim, E.Y., Connelly, J.J., Nassar, N., Kirsch, J., Winking, J., Schwarz, G., and Schindelin, H. (2006). The crystal structure of Cdc42 in complex with collybistin II, a gephyrin-interacting guanine nucleotide exchange factor. J. Mol. Biol. 359, 35-46. (A 11)

Llamas, A., Otte, T., Multhaup, G., Mendel, R.R., and Schwarz, G. (2006). The mechanism of nucleotide-assisted molybdenum insertion into molybdopterin. A novel route toward metal cofactor assembly. J. Biol. Chem. 281, 18343-18350. (A 5)

Wenz, T., Hellwig, P., MacMillan, F., Meunier, B., and Hunte, C. (2006). Probing the role of E272 in quinol oxidation of mitochondrial complex III. Biochemistry 45, 9042-9052.

Lauri, A., Shuping, X., Heidmann, I., Saedler, H., and Zachgo, S. (2006). The pollen-specific DEFH125 promoter from Antirrhinum is bound in vivo by the MADS-box proteins DEFICIENS and GLOBOSA. PLANTA 224, 61-71.

Xing, S., Lauri, A., and Zachgo, S. (2006). Redox-regulation and flower development: a novel function for glutaredoxins. Biology 8, 547-555. Review

Zachgo, S. (2006). Eine neue Funktion für Glutaredoxine in der Blütenentwicklung. Jahrbuch der MPG. Review