2014

Horn, M., Geisen, C., Becker, B., Nakamura, S., Klein, C., Cermak, L., Pagano, M., and Antebi, A. (2014). DRE-1/FBXO11 dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation. Developmental Cell 28, 697-710. Pubmed.

Boehm, V., Haberman, N., Ottens, F., Ule, J., Gehring, N.H. (2014). 3' UTR length and messenger ribonucleoprotein composition determine endocleavage efficiencies at termination codons. Cell Rep. 9(2), 555-68. Pubmed

Fatscher, T., Boehm, V., Weiche, B., Gehring, N.H. (2014). The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay. RNA. 2014 Aug 21. [Epub ahead of print] Pubmed

Clerici, M., Deniaud, A., Boehm, V., Gehring, N.H., Schaffitzel, C., and Cusack, S. (2014). Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2. Nucl. Acids Res. 42, 2673-86. PubMed

Maier, A. and Hoecker, U. (2014). COP1/SPA ubiquitin ligase complexes repress anthocyanin accumulation under low light and high light conditions. Plant Signaling & Behavior. [Epub ahead of print]

Ranjan, A., Dickopf, S., Ullrich, K.K., Rensing, S.A., Hoecker, U. (2014). Functional analysis of COP1 and SPA orthologs from Physcomitrella and rice during photomorphogenesis of transgenic Arabidopsis reveals distinct evolutionary conservation. BMC Plant Biol. 14:178. PubMed

Almontashiri, N.A.M., Chen, H.-H., Mailloux, R.J., Tatsuta, T., Teng, A.C.T., Mahmoud, A.B., Ho, T., Stewart, N.A.S., Rippstein, P., Harper, M.E., Roberts, R., Willenborg, C. and Erdmann, J. for the CARDIoGRAM Consortium, Pastore, A., McBride, H.M., Langer, T., and Stewart, A.F.R. (2014). SPG7 variant escapes phosphorylation-regulated processing by AFG3L2, elevates mitochondrial ROS, and is associated with multiple clinical phenotypes. Cell Rep. 7, 834-47. PubMed

Kondadi, A.K., Wang, S., Montagner, S., Kladt, N., Korwitz, A., Martinelli, P., Herholz, D., Baker, M.J., Schauss, A.C., Langer, T., and Rugarli, E.I. (2014). Loss of the m-AAA protease subunit AFG3L2 causes mitochondrial transport defects and tau hyperphosphorylation. EMBO J. 33, 1011-1026. PubMed

Wagner, S., Stuttmann, J., Rietz, S., Guerois, R., Brunstein, E., Bautor, J., Niefind, K., and Parker, J.E. (2014). Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity. Cell Host Microbe. 2013 Dec 11;14(6):619-30. PubMed

Tischner, C., Hofer, A., Wulff, V., Stepek, J., Dumitru, I., Becker, L., Haack, T., Kremer, L., Datta, A.N., Sperl, W., Floss, T., Wurst, W., Chrzanowska-Lightowlers, Z., de Angelis, M.H., Klopstock, T., Prokisch, H., and Wenz, T. (2014). MTO1 mediates tissue-specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention. Hum Mol Genet. pii: ddu743. [Epub ahead of print]

Becker, L., Kling, E., Schiller, E., Zeh, R., Schrewe, A., Hölter, S.M., Mossbrugger, I., Calzada-Wack, J., Strecker, V., Wittig, I., Dumitru, I., Wenz, T., Bender, A., Aichler, M., Janik, D., Neff, F., Walch, A., Quintanilla-Fend, L., Floss, T., Bekeredjian, R., Gailus-Durner, V., Fuchs, H., Wurst, W., Meitinger, T., Prokisch, H., de Angelis, M.H., and Klopstock, T. (2014). MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy. PLoS One 9(12):e114918. PubMed

Missios, P., Zhou, Y., Guachalla, L.M., von Figura, G., Wegner, A., Chakkarappan, S.R., Binz, T., Gompf, A., Hartleben, G., Burkhalter, M.D., Wulff, V., Günes, C., Sattler, R.W., Song, Z., Illig, T., Klaus, S., Böhm, B.O., Wenz, T., Hiller, K., and Rudolph, K.L. (2014). Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice. Nat Commun. 5, 4924. PubMed

Hofer, A. and Wenz, T. (2014). Post-translational modification of mitochondria as a novel mode of regulation. Exp Gerontol. 56, 202-20. PubMed 

Koenig, S., Luheshi, G.N., Wenz, T., Gerstberger, R., Roth, J., and Rummel, C. (2014). Leptin is involved in age-dependent changes in response to systemic inflammation in the rat. Brain Behav Immun. 36, 128-38. PubMed

Hofer, A., Noe, N., Tischner, C., Kladt, N., Lellek, V., Schauß, A., and Wenz, T. (2014). Defining the action spectrum of potential PGC-1? activators on a mitochondrial and cellular level in vivo. Hum Mol Genet. 23(9), 2400-15. PubMed

Peralta, S., Torraco, A., Wenz, T., Garcia, S., Diaz, F., and Moraes, C.T. (2014). Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage. Hum Mol Genet. 23(6), 1399-412. PubMed